Prowess means optimal combination of skills and knowledge?

yes in90% of situation

Language-wise, this is what I found as meaning for this word

Is this what you have in mind ?

1. 1. skill or expertise in a particular activity or field. "his prowess as a fisherman" synonyms: skill, expertise, mastery, facility, ability, capability, capacity, savoir faire, talent, genius, adeptness, aptitude, dexterity, deftness, competence, accomplishment, proficiency, finesse; More informalknow-how "his prowess as a winemaker" antonyms: inability, ineptitude
2. 2. bravery in battle. synonyms: courage, bravery, gallantry, valor, heroism, intrepidity, nerve, pluck, pluckiness, feistiness, boldness, daring, audacity,fearlessness; informalguts, spunk, moxie, grit, sand "the knight's prowess in battle"